A Conserved Serine Residue Is Required for the Phosphatidate Phosphatase Activity but Not the Transcriptional Coactivator Functions of Lipin-1 and Lipin-2

Mammalian lipins (lipin-1, lipin-2, and lipin-3) are Mg(2+)-dependent phosphatidate phosphatase (PAP) enzymes, which catalyze a key reaction in glycerolipid biosynthesis. Lipin-1 also functions as a transcriptional coactivator in conjunction with members of the peroxisome proliferator-activated rece...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Donkor, Jimmy, Zhang, Peixiang, Wong, Samantha, O'Loughlin, Lauren, Dewald, Jay, Kok, Bernard P.C., Brindley, David N., Reue, Karen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785625/
https://ncbi.nlm.nih.gov/pubmed/19717560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023663
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky