MicroRNA-137 Is a Novel Hypoxia-responsive MicroRNA That Inhibits Mitophagy via Regulation of Two Mitophagy Receptors FUNDC1 and NIX

Mitophagy receptors mediate the selective recognition and targeting of damaged mitochondria by autophagosomes. The mechanism for the regulation of these receptors remains unknown. Here, we demonstrated that a novel hypoxia-responsive microRNA, microRNA-137 (miR-137), markedly inhibits mitochondrial...

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Main Authors: Li, Wen, Zhang, Xingli, Zhuang, Haixia, Chen, He-ge, Chen, Yinqin, Tian, Weili, Wu, Wenxian, Li, Ying, Wang, Sijie, Zhang, Liangqing, Chen, Yusen, Li, Longxuan, Zhao, Bin, Sui, Senfang, Hu, Zhe, Feng, Du
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036186/
https://ncbi.nlm.nih.gov/pubmed/24573672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537050
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