MicroRNA-137 Is a Novel Hypoxia-responsive MicroRNA That Inhibits Mitophagy via Regulation of Two Mitophagy Receptors FUNDC1 and NIX

Mitophagy receptors mediate the selective recognition and targeting of damaged mitochondria by autophagosomes. The mechanism for the regulation of these receptors remains unknown. Here, we demonstrated that a novel hypoxia-responsive microRNA, microRNA-137 (miR-137), markedly inhibits mitochondrial...

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Detalles Bibliográficos
Autores principales: Li, Wen, Zhang, Xingli, Zhuang, Haixia, Chen, He-ge, Chen, Yinqin, Tian, Weili, Wu, Wenxian, Li, Ying, Wang, Sijie, Zhang, Liangqing, Chen, Yusen, Li, Longxuan, Zhao, Bin, Sui, Senfang, Hu, Zhe, Feng, Du
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036186/
https://ncbi.nlm.nih.gov/pubmed/24573672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537050
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