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Cucurbitacin I Induces Protective Autophagy in Glioblastoma in Vitro and in Vivo

There is an urgent need for new therapeutic avenues to improve the outcome of patients with glioblastoma multiforme (GBM). Current studies have suggested that cucurbitacin I, a natural selective inhibitor of JAK2/STAT3, has a potent anticancer effect on a variety of cancer cell types. This study sho...

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Autors principals: Yuan, Guang, Yan, Shao-Feng, Xue, Hao, Zhang, Ping, Sun, Jin-Tang, Li, Gang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036180/
https://ncbi.nlm.nih.gov/pubmed/24599950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.528760
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