Autophagy suppression potentiates the anti-glioblastoma effect of asparaginase in vitro and in vivo

Asparaginase has been reported to be effective in the treatment of various leukemia and several malignant solid cancers. However, the anti-tumor effect of asparaginase is always restricted due to complicated mechanisms. Herein, we investigated the mechanisms of how glioblastoma resisted asparaginase...

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Gepubliceerd in:Oncotarget
Hoofdauteurs: Chen, Qicheng, Ye, Li, Fan, Jiajun, Zhang, Xuyao, Wang, Huan, Liao, Siyang, Song, Ping, Wang, Ziyu, Wang, Shaofei, Li, Yubin, Luan, Jingyun, Wang, Yichen, Chen, Wei, Zai, Wenjing, Yang, Ping, Cao, Zhonglian, Ju, Dianwen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710905/
https://ncbi.nlm.nih.gov/pubmed/29207624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19409
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