TGF-β1 Protects against Mesangial Cell Apoptosis via Induction of Autophagy

Autophagy can lead to cell death in response to stress, but it can also act as a protective mechanism for cell survival. We show that TGF-β1 induces autophagy and protects glomerular mesangial cells from undergoing apoptosis during serum deprivation. Serum withdrawal rapidly induced autophagy within...

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Bibliographische Detailangaben
Hauptverfasser: Ding, Yan, Kim, Jin Kuk, Kim, Sung Il, Na, Hee-Jun, Jun, Soo Young, Lee, Seon Jin, Choi, Mary E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988393/
https://ncbi.nlm.nih.gov/pubmed/20876581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093724
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