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Protein Phosphatase 2A Is a Negative Regulator of Transforming Growth Factor-β1-induced TAK1 Activation in Mesangial Cells
TAK1 (transforming growth factor (TGF)-β-activated kinase 1) is a serine/threonine kinase that is rapidly activated by TGF-β1 and plays a vital function in its signal transduction. Once TAK1 is activated, efficient down-regulation of TAK1 activity is important to prevent excessive TGF-β1 responses....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447645/ https://ncbi.nlm.nih.gov/pubmed/18299321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801263200 |
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