Association of the Breast Cancer Antiestrogen Resistance Protein 1 (BCAR1) and BCAR3 Scaffolding Proteins in Cell Signaling and Antiestrogen Resistance

Most breast cancers are estrogen receptor-positive and treated with antiestrogens, but aberrant signaling networks can induce drug resistance. One of these networks involves the scaffolding protein BCAR1/p130CAS, which regulates cell growth and migration/invasion. A less investigated scaffolding pro...

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Bibliographic Details
Main Authors: Wallez, Yann, Riedl, Stefan J., Pasquale, Elena B.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036165/
https://ncbi.nlm.nih.gov/pubmed/24584939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541839
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