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Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells.

The antiestrogen tamoxifen is important in the treatment of hormone-dependent breast cancer, although development of resistance is inevitable. To unravel the molecular mechanisms of antiestrogen resistance, a search for involved genes was initiated. Retrovirus-mediated insertional mutagenesis was ap...

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Autors principals: van Agthoven, T, van Agthoven, T L, Dekker, A, van der Spek, P J, Vreede, L, Dorssers, L C
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170620/
https://ncbi.nlm.nih.gov/pubmed/9582273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.10.2799
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