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Breast Cancer Anti-estrogen Resistance 3 (BCAR3) Protein Augments Binding of the c-Src SH3 Domain to Crk-associated Substrate (p130(cas))

The focal adhesion adapter protein p130(cas) regulates adhesion and growth factor-related signaling, in part through Src-mediated tyrosine phosphorylation of p130(cas). AND-34/BCAR3, one of three NSP family members, binds the p130(cas) carboxyl terminus, adjacent to a bipartite p130(cas) Src-binding...

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Detalhes bibliográficos
Main Authors: Makkinje, Anthony, Vanden Borre, Pierre, Near, Richard I., Patel, Prayag S., Lerner, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431688/
https://ncbi.nlm.nih.gov/pubmed/22711540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.389981
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