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Nitrite Reductase and Nitric-oxide Synthase Activity of the Mitochondrial Molybdopterin Enzymes mARC1 and mARC2

Mitochondrial amidoxime reducing component (mARC) proteins are molybdopterin-containing enzymes of unclear physiological function. Both human isoforms mARC-1 and mARC-2 are able to catalyze the reduction of nitrite when they are in the reduced form. Moreover, our results indicate that mARC can gener...

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Autors principals: Sparacino-Watkins, Courtney E., Tejero, Jesús, Sun, Bin, Gauthier, Marc C., Thomas, John, Ragireddy, Venkata, Merchant, Bonnie A., Wang, Jun, Azarov, Ivan, Basu, Partha, Gladwin, Mark T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036158/
https://ncbi.nlm.nih.gov/pubmed/24500710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555177
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