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Exploring the Mechanisms of the Reductase Activity of Neuroglobin by Site-Directed Mutagenesis of the Heme Distal Pocket

[Image: see text] Neuroglobin (Ngb) is a six-coordinate globin that can catalyze the reduction of nitrite to nitric oxide. Although this reaction is common to heme proteins, the molecular interactions in the heme pocket that regulate this reaction are largely unknown. We have shown that the H64L Ngb...

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Detaylı Bibliyografya
Yayımlandı:Biochemistry
Asıl Yazarlar: Tejero, Jesús, Sparacino-Watkins, Courtney E., Ragireddy, Venkata, Frizzell, Sheila, Gladwin, Mark T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2015
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410703/
https://ncbi.nlm.nih.gov/pubmed/25554946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501196k
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