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Citrullination alters immunomodulatory function of LL-37 essential for prevention of endotoxin-induced sepsis
Cathelicidin LL-37 plays an essential role in innate immunity by killing invading microorganisms and regulating the inflammatory response. These activities depend on the cationic character of the peptide, which is conferred by arginine and lysine residues. At inflammatory foci in vivo, LL-37 is expo...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036085/ https://ncbi.nlm.nih.gov/pubmed/24771854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303062 |
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