Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences

We sequenced the genomes of 3,615 strains of serotype Emm protein 1 (M1) group A Streptococcus to unravel the nature and timing of molecular events contributing to the emergence, dissemination, and genetic diversification of an unusually virulent clone that now causes epidemic human infections world...

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Détails bibliographiques
Auteurs principaux: Nasser, Waleed, Beres, Stephen B., Olsen, Randall J., Dean, Melissa A., Rice, Kelsey A., Long, S. Wesley, Kristinsson, Karl G., Gottfredsson, Magnus, Vuopio, Jaana, Raisanen, Kati, Caugant, Dominique A., Steinbakk, Martin, Low, Donald E., McGeer, Allison, Darenberg, Jessica, Henriques-Normark, Birgitta, Van Beneden, Chris A., Hoffmann, Steen, Musser, James M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
PNAS Plus
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035937/
https://ncbi.nlm.nih.gov/pubmed/24733896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403138111
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