Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences

We sequenced the genomes of 3,615 strains of serotype Emm protein 1 (M1) group A Streptococcus to unravel the nature and timing of molecular events contributing to the emergence, dissemination, and genetic diversification of an unusually virulent clone that now causes epidemic human infections world...

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Autores principales: Nasser, Waleed, Beres, Stephen B., Olsen, Randall J., Dean, Melissa A., Rice, Kelsey A., Long, S. Wesley, Kristinsson, Karl G., Gottfredsson, Magnus, Vuopio, Jaana, Raisanen, Kati, Caugant, Dominique A., Steinbakk, Martin, Low, Donald E., McGeer, Allison, Darenberg, Jessica, Henriques-Normark, Birgitta, Van Beneden, Chris A., Hoffmann, Steen, Musser, James M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035937/
https://ncbi.nlm.nih.gov/pubmed/24733896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403138111
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