Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences

We sequenced the genomes of 3,615 strains of serotype Emm protein 1 (M1) group A Streptococcus to unravel the nature and timing of molecular events contributing to the emergence, dissemination, and genetic diversification of an unusually virulent clone that now causes epidemic human infections world...

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Hlavní autoři: Nasser, Waleed, Beres, Stephen B., Olsen, Randall J., Dean, Melissa A., Rice, Kelsey A., Long, S. Wesley, Kristinsson, Karl G., Gottfredsson, Magnus, Vuopio, Jaana, Raisanen, Kati, Caugant, Dominique A., Steinbakk, Martin, Low, Donald E., McGeer, Allison, Darenberg, Jessica, Henriques-Normark, Birgitta, Van Beneden, Chris A., Hoffmann, Steen, Musser, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035937/
https://ncbi.nlm.nih.gov/pubmed/24733896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403138111
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