Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence

Mitochondrial dynamics is crucial for the regulation of cell homeostasis. Our recent findings suggest that hepatitis C virus (HCV) promotes Parkin-mediated elimination of damaged mitochondria (mitophagy). Here we show that HCV perturbs mitochondrial dynamics by promoting mitochondrial fission follow...

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Bibliographic Details
Main Authors: Kim, Seong-Jun, Syed, Gulam H., Khan, Mohsin, Chiu, Wei-Wei, Sohail, Muhammad A., Gish, Robert G., Siddiqui, Aleem
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035934/
https://ncbi.nlm.nih.gov/pubmed/24733894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321114111
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