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Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence
Mitochondrial dynamics is crucial for the regulation of cell homeostasis. Our recent findings suggest that hepatitis C virus (HCV) promotes Parkin-mediated elimination of damaged mitochondria (mitophagy). Here we show that HCV perturbs mitochondrial dynamics by promoting mitochondrial fission follow...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035934/ https://ncbi.nlm.nih.gov/pubmed/24733894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321114111 |
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