Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1

Systemic sclerosis (SSc) is characterized by fibrosis of the skin and internal organs. The present study was undertaken to examine the effects of ciprofloxacin, a fluoroquinolone antibiotic implicated in matrix remodeling, on dermal and lung fibroblasts obtained from SSc patients. Dermal and lung fi...

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Bibliographische Detailangaben
Hauptverfasser: BUJOR, ANDREEA M., HAINES, PAUL, PADILLA, CRISTINA, CHRISTMANN, ROMY B., JUNIE, MONICA, SAMPAIO-BARROS, PERCIVAL D., LAFYATIS, ROBERT, TROJANOWSKA, MARIA
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035782/
https://ncbi.nlm.nih.gov/pubmed/23041765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2012.1150
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