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Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1

Systemic sclerosis (SSc) is characterized by fibrosis of the skin and internal organs. The present study was undertaken to examine the effects of ciprofloxacin, a fluoroquinolone antibiotic implicated in matrix remodeling, on dermal and lung fibroblasts obtained from SSc patients. Dermal and lung fi...

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Détails bibliographiques
Auteurs principaux: BUJOR, ANDREEA M., HAINES, PAUL, PADILLA, CRISTINA, CHRISTMANN, ROMY B., JUNIE, MONICA, SAMPAIO-BARROS, PERCIVAL D., LAFYATIS, ROBERT, TROJANOWSKA, MARIA
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035782/
https://ncbi.nlm.nih.gov/pubmed/23041765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2012.1150
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