Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy

Glioblastomas are the most prevalent and lethal primary brain tumor and are comprised of hierarchies with self-renewing cancer stem cells (CSCs) at the apex. Like neural stem cells (NSCs), CSCs reside in functional niches that provide essential cues to maintain the cellular hierarchy. Bone morphogen...

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Hlavní autoři: Yan, Kenneth, Wu, Qiulian, Yan, Diana H., Lee, Christine H., Rahim, Nasiha, Tritschler, Isabel, DeVecchio, Jennifer, Kalady, Matthew F., Hjelmeland, Anita B., Rich, Jeremy N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035537/
https://ncbi.nlm.nih.gov/pubmed/24788093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.235515.113
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