Secretin Stimulates Biliary Cell Proliferation by Regulating Expression of MicroRNA 125b and MicroRNA let7a in Mice

BACKGROUND & AIMS: Proliferating cholangiocytes secrete and respond to neuroendocrine hormones including secretin. We investigated whether secretin secreted by S cells and cholangiocytes stimulates biliary proliferation in mice. METHODS: Cholestasis was induced in secretin knockout (Sct(−/−)) an...

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Egile Nagusiak: Glaser, Shannon, Meng, Fanyin, Han, Yuyan, Onori, Paolo, Chow, Billy K, Francis, Heather, Venter, Julie, McDaniel, Kelly, Marzioni, Marco, Invernizzi, Pietro, Ueno, Yoshiyuki, Lai, Jia-ming, Huang, Li, Standeford, Holly, Alvaro, Domenico, Gaudio, Eugenio, Franchitto, Antonio, Alpini, Gianfranco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035389/
https://ncbi.nlm.nih.gov/pubmed/24583060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.02.030
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