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Secretin Stimulates Biliary Cell Proliferation by Regulating Expression of MicroRNA 125b and MicroRNA let7a in Mice
BACKGROUND & AIMS: Proliferating cholangiocytes secrete and respond to neuroendocrine hormones including secretin. We investigated whether secretin secreted by S cells and cholangiocytes stimulates biliary proliferation in mice. METHODS: Cholestasis was induced in secretin knockout (Sct(−/−)) an...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035389/ https://ncbi.nlm.nih.gov/pubmed/24583060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.02.030 |
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