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Gene Delivery to Overcome Astrocyte Inhibition of Axonal Growth: An In Vitro Model of the Glial Scar

After injury to the central nervous system, a glial scar develops that physically and biochemically inhibits axon growth. In the scar, activated astrocytes secrete inhibitory extracellular matrix, of which chondroitin sulfate proteoglycans (CSPGs) are considered the major inhibitory component. An in...

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Bibliografiska uppgifter
Huvudupphovsmän: Tuinstra, Hannah M., Ducommun, Melissa M., Briley, William E., Shea, Lonnie D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035246/
https://ncbi.nlm.nih.gov/pubmed/23055330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.24750
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