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Disruption of spinal cord white matter and sciatic nerve geometry inhibits axonal growth in vitro in the absence of glial scarring

BACKGROUND: Axons within the mature mammalian central nervous system fail to regenerate following injury, usually resulting in long-lasting motor and sensory deficits. Studies involving transplantation of adult neurons into white matter implicate glial scar-associated factors in regeneration failure...

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Autori principali: Pettigrew, David B, Shockley, Kristina P, Crutcher, Keith A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC32296/
https://ncbi.nlm.nih.gov/pubmed/11399204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-2-8
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