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Measurement of protein farnesylation and geranylgeranylation in vitro, in cultured cells and in biopsies, and the effects of prenyl transferase inhibitors
The importance of the post-translational lipid modifications farnesylation and geranylgeranylation in protein localization and function coupled with the critical role of prenylated proteins in malignant transformation has prompted interest in their biology and the development of farnesyl transferase...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035200/ https://ncbi.nlm.nih.gov/pubmed/22036881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.387 |
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