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Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1

Caveolin-1 (Cav-1) is a major structural protein in caveolae in the plasma membranes of many cell types, particularly endothelial cells and adipocytes. Loss of Cav-1 function has been implicated in multiple diseases affecting the cardiopulmonary and central nervous systems, as well as in specific as...

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Autors principals: Mundy, Dorothy I., Lopez, Adam M., Posey, Kenneth S., Chuang, Jen-Chieh, Ramirez, Charina M., Scherer, Philipp E., Turley, Stephen D.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035115/
https://ncbi.nlm.nih.gov/pubmed/24747682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.04.002
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