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Endogenous lipid activated G protein-coupled receptors: Emerging structural features from crystallography and molecular dynamics simulations
Class A G-protein coupled receptors (GPCRs) are thought to have a common topology that includes seven transmembrane alpha helices (TMHs) that are arranged to form a closed bundle. This bundle forms the ligand binding pocket into which ligands are commonly thought to enter via the extracellular milie...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034697/ https://ncbi.nlm.nih.gov/pubmed/23485612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2013.01.009 |
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