Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency

Pigs with severe combined immunodeficiency (SCID) may provide useful models for regenerative medicine, xenotransplantation, and tumor development and will aid in developing therapies for human SCID patients. Using a reporter-guided transcription activator-like effector nuclease (TALEN) system, we ge...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Kiho, Kwon, Deug-Nam, Ezashi, Toshihiko, Choi, Yun-Jung, Park, Chankyu, Ericsson, Aaron C., Brown, Alana N., Samuel, Melissa S., Park, Kwang-Wook, Walters, Eric M., Kim, Dae Young, Kim, Jae-Hwan, Franklin, Craig L., Murphy, Clifton N., Roberts, R. Michael, Prather, Randall S., Kim, Jin-Hoi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034252/
https://ncbi.nlm.nih.gov/pubmed/24799706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406376111
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