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Recombination activating gene-2(null) severe combined immunodeficient pigs and mice engraft human induced pluripotent stem cells differently

This study comparatively investigated the transcriptional, physiological, and phenotypic differences of the immune disorder between severe combined immunodeficient (SCID) mouse and pig models. We discovered that the recombination activating gene-2 (Rag-2) SCID mice, but not RAG-2 SCID pigs, showed i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Choi, Yun-Jung, Kim, EunSu, Reza, Abu Musa Md Talimur, Hong, Kwonho, Song, Hyuk, Park, Chankyu, Cho, Seong-Keun, Lee, Kiho, Prather, Randall S., Kim, Jin-Hoi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642487/
https://ncbi.nlm.nih.gov/pubmed/29050212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20626
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