Evolution of the primate trypanolytic factor APOL1

ApolipoproteinL1 (APOL1) protects humans and some primates against several African trypanosomes. APOL1 genetic variants strongly associated with kidney disease in African Americans have additional trypanolytic activity against Trypanosoma brucei rhodesiense, the cause of acute African sleeping sickn...

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Dades bibliogràfiques
Autors principals: Thomson, Russell, Genovese, Giulio, Canon, Chelsea, Kovacsics, Daniella, Higgins, Matthew K., Carrington, Mark, Winkler, Cheryl A., Kopp, Jeffrey, Rotimi, Charles, Adeyemo, Adebowale, Doumatey, Ayo, Ayodo, George, Alper, Seth L., Pollak, Martin R., Friedman, David J., Raper, Jayne
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034216/
https://ncbi.nlm.nih.gov/pubmed/24808134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400699111
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