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Unlocking the Door to Neuronal Woes in Alzheimer’s Disease: Aβ and Mitochondrial Permeability Transition Pore

Mitochondrial dysfunction occurs early in the progression of Alzheimer’s disease. Amyloid-β peptide has deleterious effects on mitochondrial function and contributes to energy failure, respiratory chain impairment, neuronal apoptosis, and generation of reactive oxygen species in Alzheimer’s disease....

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Main Authors: Du, Heng, Yan, Shirley ShiDu
格式: Artigo
語言:Inglês
出版: MDPI 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033960/
https://ncbi.nlm.nih.gov/pubmed/27713335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3061936
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