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Pathogenic potential of interferon αβ in acute influenza infection
Influenza symptoms vary from mild disease to death; however, determinants of severity are unclear. Type I interferons (IFNαβ) are recognized as key antiviral cytokines. Here we show that, surprisingly, influenza-infected 129 mice have increased lung damage, morbidity and mortality, yet higher levels...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Pub. Group
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4033792/ https://ncbi.nlm.nih.gov/pubmed/24844667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4864 |
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