Pathogenic potential of interferon αβ in acute influenza infection

Influenza symptoms vary from mild disease to death; however, determinants of severity are unclear. Type I interferons (IFNαβ) are recognized as key antiviral cytokines. Here we show that, surprisingly, influenza-infected 129 mice have increased lung damage, morbidity and mortality, yet higher levels...

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Hlavní autoři: Davidson, Sophia, Crotta, Stefania, McCabe, Teresa M, Wack, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033792/
https://ncbi.nlm.nih.gov/pubmed/24844667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4864
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