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Diastereoselective Three-Component Synthesis of β-Amino Carbonyl Compounds Using Diazo Compounds, Boranes, and Acyl Imines under Catalyst-Free Conditions

[Image: see text] Diazo compounds, boranes, and acyl imines undergo a three-component Mannich condensation reaction under catalyst-free conditions to give the anti β-amino carbonyl compounds in high diastereoselectivity. The reaction tolerates a variety of functional groups, and an asymmetric varian...

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Detalhes bibliográficos
Main Authors: Luan, Yi, Yu, Jie, Zhang, Xiaowei, Schaus, Scott E., Wang, Ge
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033649/
https://ncbi.nlm.nih.gov/pubmed/24787904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo5003505
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