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Cellular unfolded protein response against viruses used in gene therapy

Viruses are excellent vehicles for gene therapy due to their natural ability to infect and deliver the cargo to specific tissues with high efficiency. Although such vectors are usually “gutted” and are replication defective, they are subjected to clearance by the host cells by immune recognition and...

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Detalles Bibliográficos
Main Authors: Sen, Dwaipayan, Balakrishnan, Balaji, Jayandharan, Giridhara R.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033601/
https://ncbi.nlm.nih.gov/pubmed/24904562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00250
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