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The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines

All of the over 1 million total joint replacements implanted in the US each year are expected to eventually fail after 15–25 years of use, due to slow progressive subtle inflammation at the bone implant interface. This inflammatory disease state is caused by implant debris acting, primarily, on inna...

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Detalhes bibliográficos
Main Authors: Landgraeber, Stefan, Jäger, Marcus, Jacobs, Joshua J., Hallab, Nadim James
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033543/
https://ncbi.nlm.nih.gov/pubmed/24891761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/185150
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