Cobalt Alloy Implant Debris Induces Inflammation and Bone Loss Primarily through Danger Signaling, Not TLR4 Activation: Implications for DAMP-ening Implant Related Inflammation

Cobalt alloy debris has been implicated as causative in the early failure of some designs of current total joint implants. The ability of implant debris to cause excessive inflammation via danger signaling (NLRP3 inflammasome) vs. pathogen associated pattern recognition receptors (e.g. Toll-like rec...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Samelko, Lauryn, Landgraeber, Stefan, McAllister, Kyron, Jacobs, Joshua, Hallab, Nadim James
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965114/
https://ncbi.nlm.nih.gov/pubmed/27467577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160141
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk