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The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines

All of the over 1 million total joint replacements implanted in the US each year are expected to eventually fail after 15–25 years of use, due to slow progressive subtle inflammation at the bone implant interface. This inflammatory disease state is caused by implant debris acting, primarily, on inna...

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Hlavní autoři: Landgraeber, Stefan, Jäger, Marcus, Jacobs, Joshua J., Hallab, Nadim James
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033543/
https://ncbi.nlm.nih.gov/pubmed/24891761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/185150
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