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Cutting Edge: Innate memory CD8(+) T cells are distinct from homeostatic expanded CD8(+) T cells and rapidly respond to primary antigenic stimuli

Innate memory phenotype (IMP) CD8(+) T cells are non-conventional αβ T cells exhibiting features of innate immune cells, and are significantly increased in the absence of ITK. Their developmental path and function are not clear. Here we show hematopoietic MHCI dependent generation of antigen specifi...

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Hlavní autoři: Huang, Weishan, Hu, Jianfang, August, Avery
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033301/
https://ncbi.nlm.nih.gov/pubmed/23408840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202988
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