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Naïve and Innate Memory phenotype CD4(+) T-cells have different requirements for active Itk for their development

The Tec family kinase Itk regulates the development of conventional and innate CD8(+) T cells, however little is known about the role of Itk in the development of CD4(+) T cell lineages, although the role of Itk in the T cell activation and function is well defined. We show here that the Itk null mi...

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Detalhes bibliográficos
Main Authors: Hu, Jianfang, August, Avery
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836934/
https://ncbi.nlm.nih.gov/pubmed/18453573
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