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Memory phenotype CD8(+) T-cells with innate function selectively develop in the absence of active Itk
T cells with a memory like phenotype and possessing innate immune function have been previously identified as CD8(+)CD44(hi) cells. These cells rapidly secrete IFNγ upon stimulation with IL-12/IL-18 and are involved in innate responses to infection with Listeria monocytogenes. The signals regulating...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770953/ https://ncbi.nlm.nih.gov/pubmed/17724684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737311 |
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