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Memory phenotype CD8(+) T-cells with innate function selectively develop in the absence of active Itk

T cells with a memory like phenotype and possessing innate immune function have been previously identified as CD8(+)CD44(hi) cells. These cells rapidly secrete IFNγ upon stimulation with IL-12/IL-18 and are involved in innate responses to infection with Listeria monocytogenes. The signals regulating...

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Detalhes bibliográficos
Main Authors: Hu, Jianfang, Sahu, Nisebita, Walsh, Elizabeth, August, Avery
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770953/
https://ncbi.nlm.nih.gov/pubmed/17724684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737311
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