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Dendritic cell-MHCII and Itk regulate functional development of regulatory innate memory CD4(+) T cells in bone marrow transplantation()

MHCII-influenced CD4(+) T cell differentiation and function play critical roles in regulating the development of autoimmunity. The lack of hematopoietic MHCII causes autoimmune disease that leads to severe wasting in syngeneic recipients. Using murine models of bone marrow transplantation (BMT), we...

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Autori principali: Huang, Weishan, Qi, Qian, Hu, Jianfang, Huang, Fei, Laufer, Terri M., August, Avery
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033297/
https://ncbi.nlm.nih.gov/pubmed/24610010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303176
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