Biomarkers of Safety and Immune Protection for Genetically Modified Live Attenuated Leishmania Vaccines Against Visceral Leishmaniasis – Discovery and Implications

Despite intense efforts there is no safe and efficacious vaccine against visceral leishmaniasis, which is fatal and endemic in many tropical countries. A major shortcoming in the vaccine development against blood-borne parasitic agents such as Leishmania is the inadequate predictive power of the ear...

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Main Authors: Gannavaram, Sreenivas, Dey, Ranadhir, Avishek, Kumar, Selvapandiyan, Angamuthu, Salotra, Poonam, Nakhasi, Hira L.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2014
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033241/
https://ncbi.nlm.nih.gov/pubmed/24904589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00241
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