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Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons

ClC-3 is a member of the CLC family of anion channels and transporters that localizes to early and late endosomes as well as to synaptic vesicles (SV). Its genetic disruption in mouse models results in pronounced hippocampal and retinal neurodegeneration, suggesting that ClC-3 might be important for...

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Autors principals: Guzman, Raul E., Alekov, Alexi K., Filippov, Mikhail, Hegermann, Jan, Fahlke, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033211/
https://ncbi.nlm.nih.gov/pubmed/24904288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00143
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