A non-inferiority trial of an attenuated combination strategy (‘COBRA-light’) compared to the original COBRA strategy: clinical results after 26 weeks

BACKGROUND: Early, intensive treatment of rheumatoid arthritis (RA) with the combination of (initially high dose) prednisolone, methotrexate and sulfasalazine (COBRA therapy) considerably lowers disease activity and suppresses radiological progression, but is infrequently prescribed in daily practic...

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Dades bibliogràfiques
Autors principals: den Uyl, Debby, ter Wee, Marieke, Boers, Maarten, Kerstens, Pit, Voskuyl, Alexandre, Nurmohamed, Mike, Raterman, Hennie, van Schaardenburg, Dirkjan, van Dillen, Nancy, Dijkmans, Ben, Lems, Willem
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2014
Matèries:
Clinical and Epidemiological Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033113/
https://ncbi.nlm.nih.gov/pubmed/23606682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2012-202818
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