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Why are Dutch rheumatologists reluctant to use the COBRA treatment strategy in early rheumatoid arthritis?

BACKGROUND: The Combinatietherapie Bij Reumatoide Artritis (COBRA) trial has proved that combination therapy with prednisolone, methotrexate and sulphasalazine is superior to sulphasalazine monotherapy in suppressing disease activity and radiological progression of early rheumatoid arthritis (RA). I...

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Detalhes bibliográficos
Main Authors: van Tuyl, Lilian H D, Plass, Anne Marie C, Lems, Willem F, Voskuyl, Alexandre E, Dijkmans, Ben A C, Boers, Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955117/
https://ncbi.nlm.nih.gov/pubmed/17392349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.067447
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