Luteolin and Quercetin Affect the Cholesterol Absorption Mediated by Epithelial Cholesterol Transporter Niemann–Pick C1-Like 1 in Caco-2 Cells and Rats

Niemann–Pick C1-Like 1 (NPC1L1) mediates cholesterol absorption, and ezetimibe is a potent NPC1L1 inhibitor applicable for medication of hypercholesterolemia. Epidemiological studies demonstrated that consumption of polyphenols correlates with a decreased risk for atherosclerosis due to their antiox...

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Bibliographic Details
Main Authors: Nekohashi, Mari, Ogawa, Mana, Ogihara, Takuo, Nakazawa, Kyoko, Kato, Hisanori, Misaka, Takumi, Abe, Keiko, Kobayashi, Shoko
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032257/
https://ncbi.nlm.nih.gov/pubmed/24859282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097901
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