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Evidence from molecular dynamics simulations of conformational preorganization in the ribonuclease H active site

Ribonuclease H1 (RNase H) enzymes are well-conserved endonucleases that are present in all domains of life and are particularly important in the life cycle of retroviruses as domains within reverse transcriptase. Despite extensive study, especially of the E. coli homolog, the interaction of the high...

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Hlavní autoři: Stafford, Kate A., Palmer III, Arthur G.
Médium: Artigo
Jazyk:Inglês
Vydáno: F1000Research 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032109/
https://ncbi.nlm.nih.gov/pubmed/25075292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.3605.1
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