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Evidence from molecular dynamics simulations of conformational preorganization in the ribonuclease H active site
Ribonuclease H1 (RNase H) enzymes are well-conserved endonucleases that are present in all domains of life and are particularly important in the life cycle of retroviruses as domains within reverse transcriptase. Despite extensive study, especially of the E. coli homolog, the interaction of the high...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
F1000Research
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4032109/ https://ncbi.nlm.nih.gov/pubmed/25075292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.3605.1 |
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