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Thermostability of Enzymes from Molecular Dynamics Simulations

Thermodynamic stability is a central requirement for protein function and one goal of protein engineering is improvement of stability, particularly for applications in biotechnology. Herein, molecular dynamics simulations are used to predict in vitro thermostability of members of the bacterial Ribon...

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Détails bibliographiques
Publié dans:J Chem Theory Comput
Auteurs principaux: Zeiske, Tim, Stafford, Kate A., Palmer, Arthur G.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977845/
https://ncbi.nlm.nih.gov/pubmed/27123810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b00120
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