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Pharmacological Inhibition of Bromodomain-Containing Proteins in Inflammation

Inflammation is associated with the activation of genes that contribute to immune defense and tissue repair. The bromodomain-containing proteins of the BET family, which recognize histone lysine acetylation, play a key role in the transcriptional control of inflammatory genes. Inhibition of BET prot...

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Detalhes bibliográficos
Autor principal: Schaefer, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031962/
https://ncbi.nlm.nih.gov/pubmed/24890512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a018671
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